Taconic Biosciences Adds New Humanized Immune System (HIS) Model to Its Portfolio For Immuno-Oncology Research

New huNOG-EXL EA Model Extends Study Windows Significantly

RENSSELAER, N.Y., Jan. 18, 2022 (GLOBE NEWSWIRE) — Taconic Biosciences, a global leader in providing drug discovery animal model solutions, announces the launch of the huNOG-EXL EA (Early Access) humanized immune system (HIS) mouse. This product expands Taconic’s widely used HIS portfolio. huNOG-EXL EA significantly lengthens the study window during which a myeloid-lineage HIS mouse model can be used successfully.

Taconic’s huNOG-EXL models support human myeloid and lymphoid cells, making these mice especially useful for immuno-oncology research and other immune-related applications. With the longest lifespan of any myeloid-supportive HIS model, the original huNOG-EXL model (now called huNOG-EXL SA, or Standard Access) has been successfully applied in preclinical drug discovery research since 2016. The huNOG-EXL SA model is provided after a quality control step at 10 weeks post-engraftment. Feedback from users suggests research applications requiring particularly long study timelines or importation into regions with long quarantine periods present experimental and logistical hurdles that can limit the utility of the Standard Access (SA) model.

The new huNOG-EXL EA model removes those challenges by providing access to huNOG-EXL mice soon after engraftment, extending the useful study window. This makes the huNOG-EXL EA ideal for engraftment of slow-growing tumors, longer treatment paradigms, or various study customizations. Early access to an extended myeloid lineage model is also advantageous to researchers who face model importation quarantines, which would otherwise consume a significant portion of the useful study window for these mice. Because the huNOG-EXL EA model is shipped before an engraftment QC step is possible, it is made using cells from donors previously validated to engraft well so as to reduce the risk of engraftment failures.

“The huNOG-EXL EA model meets critical scientific needs for investigators performing immuno-oncology research or studying other immune-related diseases,” said Dr. Michael Seiler, vice president of commercial products at Taconic. “After conducting extensive research and development, along with rigorous beta testing with several industry partners, Taconic is excited to now offer the new model and expand the usefulness of this unique humanized mouse.”

To learn more about Taconic’s huNOG-EXL EA model, please contact us at 1-888-TACONIC (888-822-6642) in the US, +45 70 23 04 05 in Europe, or email info@taconic.com.

About Taconic Biosciences, Inc.

Taconic Biosciences is a fully licensed, global leader in genetically engineered rodent models and services. Founded in 1952, Taconic provides the best animal solutions so that customers can acquire, custom-generate, breed, precondition, test, and distribute valuable research models worldwide. Specialists in genetically engineered mouse and rat models, microbiome, immuno-oncology mouse models, and integrated model design and breeding services, Taconic operates three service laboratories and six breeding facilities in the U.S. and Europe, maintains distributor relationships in Asia and has global shipping capabilities to provide animal models almost anywhere in the world.

Media Contact:

Nancy J Sandy

CEO

608-332-6320

Nancy.Sandy@taconic.com

OKX overtakes global crypto exchanges as 2nd largest, rebrands as cross-platform services provider

Formerly OKEx, OKX’s new brand highlights the platform’s robust suite of crypto, NFT and DeFi investing products

VICTORIA, Seychelles, Jan. 18, 2022 (GLOBE NEWSWIRE) — OKX, which recently became the second largest cryptocurrency exchange in the world by spot trading volume, today announced a company-wide rebrand that reflects the dynamism and accelerating adoption of cryptocurrency. Founded in 2017 as a cryptocurrency trading service, OKX has since amassed over 20 million users and expanded its suite of digital asset investing products to include OKX Earn, a tool for earning passive crypto income; an NFT marketplace and decentralized application discovery hub; and most recently, MetaX, OKX’s new decentralized mode that features a cross-chain dashboard and self-custody Web 3.0 wallet for storing digital assets, including NFTs.

This shift, as highlighted by the company’s name change from OKEx to OKX, reflects the platform’s growing number of wealth creation opportunities beyond the exchange, which investors use to trade hundreds of digital assets on spot, margin and derivatives markets.

As part of the move, OKX has declared its mission to be “to remove barriers to wealth creation by giving you access to everything our decentralized future holds.” This underscores the platform’s ongoing evolution towards decentralization, which includes giving investors the option to self-custody their digital assets. Distinct from other centralized cryptocurrency exchanges, OKX is committed to gradually decreasing the company’s level of involvement in user activity, with the ultimate goal of shedding intermediation entirely.

“OKX is moving beyond the standard centralized exchange model to give our customers an end-to-end cryptocurrency experience,” said Jay Hao, CEO of OKX. “Most importantly, we’re doing this while upholding the core principles of crypto — decentralization and autonomy. Our goal is to give customers the tools they need to easily and securely earn, transfer, and spend their wealth as they see fit, without intermediation from us. We’ve dropped the ‘E’ from our name because we’re so much more than an exchange, just like crypto is so much more than a speculative asset.”

OKX, which lists over 250 digital assets and has long held the #1 rank for cryptocurrency futures trading volumes, recently became the second largest cryptocurrency spot trading platform in the world. In 2021, total trading volume on the platform, including spot and derivatives instruments, grew over 700%, while the number of trades executed on the platform increased over 480%. Staking, savings and DeFi offerings via OKX Earn saw over $5.1 billion deposited by users, and paid out over $314 million in passive income this past year.

To learn more, please visit OKX.com and follow @OKX on Twitter.

About OKX

Founded in 2017, OKX is a world leading cryptocurrency exchange and ecosystem. OKX has innovatively adopted blockchain technology to reshape the financial ecosystem and offers some of the most diverse and sophisticated products, solutions and trading tools on the market. Trusted by more than 20 million people in 180 regions across the globe, OKX’s mission is to remove barriers to wealth creation by offering access to everything the decentralized future holds. With its unwavering commitment to innovation, OKX envisions a world of financial inclusion for all through the power of crypto and decentralized finance.

Contact us

Email: media@okx.com
Olivia Capozzalo:
olivia.capozzalo@okx.com
@oliviacap (Telegram)

Corporate Briefing Session of Jauharabad Sugar Mills Limited

Karachi, Jauharabad Sugar Mills Limited informed Pakistan Stock Exchange that the corporate briefing session of the company will be held on January 28, 2022 at Lahore for the year ended September 30, 2021, to brief the analysts/shareholders/ investors about the company’s financial results and future outlook.

Jauharabad Sugar Mills Limited (Formerly “Kohinoor Sugar Mills Limited”) is a public limited company, and has an honor of being one of the pioneer sugar mills of Pakistan, established since independence at Jauharabad, District Khushab in the Punjab Province by the Thal Development Authority. The Company has designed crushing capacity of 8000 MT of sugar cane per day. Cane Processing (Pvt) Limited acquired the majority shares from Saigol family under sales purchase agreement dated October 14, 2013.The new management took the control of the Company after the approval of acquisition of majority voting shares and control of the company by the Securities and Exchange Commission of Pakistan. The Company’s name has also been changed to “Jauharabad Sugar Mills Limited” with effect from August 27, 2014. The new management has removed the bottlenecks of the plant and is focused to revitalize the project.

The symbol “JSML” is being used by the stock exchanges for the shares Jauharabad Sugar Mills Limited.

Transaction of 700 shares of Packages Limited

Karachi, Packages Limited informed Pakistan Stock Exchange about transaction of shares of the company. 700 shares @ Rs. 490.00 per share were bought from the market on January 17, 2022 through CDC.

Packages Limited is a public limited company incorporated in Pakistan. It is principally engaged in the manufacture and sale of packaging materials and tissue products. The Company also holds investments in companies.

The total numbers of shares are 89,379,504. The Earnings per share is 31.55 in 2020 which was 15.06 in 2019. The Profit after Taxation of the Company is 2,819,524,000 in 2020 which was 1,346,303,000 in 2019.

Unusual Movement in Price or Volume of Modaraba Al-Mali

Karachi, Modaraba Al-Mali informed Pakistan Stock Exchange that in terms of section 97 of the securities Act, 2015 and clause 5.6.3 of Pakistan Stock Exchange Regulations, the Modaraba has duly communicated all price sensitive and material information which is required to be disclosed in terms of clause 5.6.3 of the PSX Regulations to the exchange on timely basis.

Modaraba Al-Mali is a multipurpose and perpetual Modaraba floated in Pakistan on July 8, 1987 and is managed by BankIslami Modaraba Investments Limited. The Modaraba is engaged in the business of leasing, murabaha, musharaka financing, operation of petrol and diesel filling/service station. The Modaraba is listed at Pakistan Stock Exchange.

The total number of shares are 18,423,945. The Earnings per share is 1.01 in 2020 which was 0.43 in 2019. The Profit after taxation is 18,607,000 in 2020 which was 7,965,000 in 2019.

Transmission of Quarterly Report for the Period Ended September 30, 2021 of Data Textiles Limited

Karachi, Data Textiles Limited informed Pakistan Stock Exchange that Quarterly Report of the Company for the period ended September 30, 2021 have been transmitted through PUCARS and is also available on Company’s website.

Data Textiles started commercial operations in October 1991.The main activity of the company is manufacturing and sale of yarn. The total numbers of shares are 9,909,600. The Earnings per share is (0.03) in 2020 which was (0.03) in 2019. The Company had a loss of Rs. 2,541,000 in 2020 which was 2,530,000 in 2019.

Unusual Movement in Price or Volume of First IBL Modaraba

Karachi, First IBL Modaraba informed Pakistan Stock Exchange that neither the company has decided to undertake any project or nor there is any other development that may impact the share price of the FIBLM, they understand that this is a clear case of manipulation from some market participants as price of the share has increased significantly.

Established in 1989, First IBL Modaraba (formerly First Sanaullah Modaraba) is one of the oldest, yet resilient Modarabas of the Islamic Financial sector of Pakistan. With over three decades of experience, and management consisting of expert and veteran bankers, we continue to provide Islamic Financial products to the corporate sector as well as individual consumers.

Their clientele ranges from renowned Construction & Engineering Companies, Textile Companies, Power Generation Companies, Cement Manufacturing Companies, Educational Sector, Universities and Group Companies to individuals. So be it a facility for an individual, working capital for a business, house loans or term leases for vehicles and machinery, and have a specialized, customized and fulfilling – yet Islamic – product for your need.

The total number of shares are 21,687,500. The Earnings per share is 0.19 in 2020 which was 0.22 in 2019. The Profit after Taxation of the Company is 4,003,000 in 2020 which was 4,708,000 in 2019.

Election of Directors of Al-Abbas Sugar Mills Limited

Karachi, Al-Abbas Sugar Mills Limited informed Pakistan Stock Exchange that the eight members have filed with the company of their intention to offer themselves for election as Directors at the Annual General Meeting of the company to be held on January 26, 2022.

Al-Abbas Sugar Mills Limited was incorporated in May 1991 and was listed in on April 1992 at the Karachi Stock Exchange Limited.

The company has two major units located at Mirwah Gorchani and Dhabeji Thatta. The unit is located at Mirwah Gorchani with installed sugarcane crushing capacity of 8,500 Tons per day and processing capacity of molasses into quality industrial alcohol of 170,000 liters per day. The other unit is located at Dhabeji Thatta and has capacity to manufacture 27,220 M.T of different alloys per annum. The tank terminal unit of the Company is located at Kemari Karachi with storage capacity of 34,900 M.T of liquids.

AL-Abbas Sugar Mills was started the sugar production in 1994 industrial alcohol in 2000, alloys in 2005 and power generation in 2010. Also major chunk of our alcohol production is being exported to Europe, Japan, UAE, Saudi Arabia and Philippine.

As part of Company strategic planning, the Company acquired Al-Abbas Industries Limited in 2007. At that time Al-Abbas Industries Limited have one of the country’s biggest medium density fibre board plant, manufacturing facilities to produce various types of alloys product to meet the whole country demand, and 15 MW captive power plant. Subsequently, the Al-Abbas Industries Limited merged into the Al-Abbas Sugar Mills Limited.

The total number of shares company has issued are 17,362,300, where earning Per Shares (EPS) was 71.67 in 2020 and in 2019 it was 64.05 per share. The Profit After Tax has increased up to 1,244,347,000 in 2020 which was 1,111,978,000 in 2019.

Appointment of Chairman and Chief Executive Officer of TRG Pakistan Limited

Karachi, TRG Pakistan Limited informed Pakistan Stock Exchange that Mr. Waleed Tariq Saigol has been appointed as Chairman of the company with effect from January 14, 2022 in place of Mr. Peter H.R. Riepenhausen and Mr. Hasnain Aslam has been appointed as Chief Executive Officer of the company with effect from January 17, 2022.

TRG Pakistan Limited was incorporated in Pakistan as a public limited company on December 2, 2002. The principal activity of the Company is to act as a holding company. The Parent Company, (through its subsidiary, The Resource Group International Limited) has a portfolio of investments primarily in the Technology, IT Enabled Services and Medicare Insurance sectors.

TRG obtained the certificate of commencement of business on February 27, 2003. The operations of the Company effectively started on April 11, 2003.

The total number of shares of the Company is 545,390,665. The Earning per share is 0.14 in 2020 which was 0.00 in 2019. The Profit after tax is 76,165,000 in 2020 which was 1,855,000 in 2019.

Corporate Briefing Session of J. D. W. Sugar Mills Limited

Karachi, J. D. W. Sugar Mills Limited informed Pakistan Stock Exchange that the corporate briefing session of the company will be held on January 28, 2022 at Lahore, to brief the analysts/investors/shareholders about the company’s financial results and future outlooks.

The Sugar Division comprises of three sugar mills Units in the districts of Rahim Yar Khan, Punjab and Ghotki, Sindh. With its combined crushing capacity of 44,500 TCD, it is one of the largest group in the sugar sector and contributes approximately 15-17% of country’s sugar production.

The Company has been successful in completing and commissioning its two high-pressure Co-Generation plants at Unit-II (Sadiqabad) and Unit-III (Ghoki). The first 26.6 MW plant at Unit-II achieved commercial operations on 12 June 2014 after clearing all testing, certification and trial run requirements. The second 26.8 MW project at Unit-III achieved commercial operations on 03 October 2014 after similarly completing all pre-commissioning formalities.

JDW is also managing Sugarcane Corporate Farms over the area of 24,000 Acres in the Provinces of Punjab & Sindh. By using knowledge, experience together with modern tools and machinery and distinctive agronomic strategies, JDW has been able to build highly efficient and eco-friendly farms with higher yields. Company’s unique farming techniques have also led to the capacity building of existing farmers thereby resulting in improved and reliable cane supply to JDW.

The symbol “JDWS” is being used by the stock exchange for the shares of J. D. W. Sugar Mills Limited.

Transaction of 10,126 shares of Macter International Limited

Karachi, Macter International Limited informed Pakistan Stock Exchange about transaction of shares of the company. 10,126 shares @ Rs. 165.00 per share were sold in the market on January 17, 2022 through NDM.

Macter International Limited was incorporated in Pakistan in 1992 as a private limited company and was converted into a public limited company in 2011. The principal activity of the company is to manufacture and market pharmaceutical products.

The total numbers of shares are 39,144,351. The earnings per share is 0.38 in 2020. The Profit after Taxation is 14,930,000 in 2020.

Notice of Emergent meeting of Board of directors of Dost Steels Limited

Karachi, Dost Steels Limited informed Pakistan Stock Exchange that board of directors meeting of the company will be held on January 18, 2022 at Lahore. The agenda of the meeting will to consider and approve issuance of up to 29% shares by way of issue of shares other than rights offer mechanism to potential Investors (including his nominees) under the provisions of section 83 and subject to the pricing of such issue of shares under the provisions of Section 82 of the companies Act 2017, Increase in authorized share capital of the company and to provide necessary authority to the chief executive Officer of the company to complete all necessary corporate, regulatory and legal formalities including execution of necessary documents, approval from the shareholders of the company, lenders approvals and the securities and Exchange commission of Pakistan.

Further, the company has declared the closed period from November 01, 2021 to November 01, 2021.

Dost Steels Limited is a company incorporated in Pakistan on March 19, 2004. The principal business of the company include manufacturing of steel, direct reduced iron, sponge iron, hot briquetted iron, carbon steel, pig iron and special alloy steel in different forms. Dost Steels Limited was converted into public limited company with effect from May 20, 2006. The registered office of the company is located at Karachi.

The Company’s mill has a capacity of approximately 350,000 tons per annum, which produces hot rolled high tensile, deformed steel bars of sizes ranging from 8 millimeters to 50 millimeters in length, over 12 meters in bundles and approximately 2,000 kilograms using THERMEX Bar Quenching process.

The Shares of the company are 315,733,860. The Earnings per shares of the company is (0.76) in 2020 which was (0.99) in 2019. The Company had a loss of 241,106,000 in 2020 which was 313,309,000 in 2019.